PHPMailer 6.4.1 and earlier contain a vulnerability that can result in untrusted code being called (if such code is injected into the host project's scope by other means). If the $patternselect parameter to validateAddress() is set to 'php' (the default, defined by PHPMailer::$validator), and the global namespace contains a function called php, it will be called in preference to the built-in validator of the same name. Mitigated in PHPMailer 6.5.0 by denying the use of simple strings as validator function names.
PHPMailer before 6.1.6 contains an output escaping bug when the name of a file attachment contains a double quote character. This can result in the file type being misinterpreted by the receiver or any mail relay processing the message.