Flask-AppBuilder is an application development framework. Prior to 4.5.3, Flask-AppBuilder allows unauthenticated users to enumerate existing usernames by timing the response time from the server when brute forcing requests to login. This vulnerability is fixed in 4.5.3.
Flask-AppBuilder versions before 4.3.0 lack rate limiting which can allow an attacker to brute-force user credentials. Version 4.3.0 includes the ability to enable rate limiting using `AUTH_RATE_LIMITED = True`, `RATELIMIT_ENABLED = True`, and setting an `AUTH_RATE_LIMIT`.