OpenVPN versions before 2.3.15 and before 2.4.2 are vulnerable to reachable assertion when packet-ID counter rolls over resulting into Denial of Service of server by authenticated attacker.
OpenVPN, when using a 64-bit block cipher, makes it easier for remote attackers to obtain cleartext data via a birthday attack against a long-duration encrypted session, as demonstrated by an HTTP-over-OpenVPN session using Blowfish in CBC mode, aka a "Sweet32" attack.
The openvpn_decrypt function in crypto.c in OpenVPN 2.3.0 and earlier, when running in UDP mode, allows remote attackers to obtain sensitive information via a timing attack involving an HMAC comparison function that does not run in constant time and a padding oracle attack on the CBC mode cipher.